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Bio-stimulating fillers, also known as collagen-stimulating fillers or dermal stimulators, are a type of injectable filler used to enhance the appearance of the skin by stimulating the production of collagen. These fillers typically contain biocompatible substances such as calcium hydroxyapatite, poly-L-lactic acid, or polycaprolactone, which are designed to trigger the body’s natural collagen-building response.

When bio-stimulating fillers are injected into the skin, they stimulate fibroblast cells to produce new collagen fibers, resulting in improved skin elasticity, texture, and volume. Over time, as the body gradually breaks down the filler material, the newly formed collagen provides long-lasting results.

Frequently Asked Questions


Results may be seen in 6 weeks and will continue to improve over 2 to 6 months. While the threads slowly dissolve, their effects may last up to 12 months.


Collagen-stimulating injections can be used on various areas of the face, including the cheeks, temples, jawline, and nasolabial folds. They can also be used on other areas of the body, such as the neck, décolletage, and hands.


Like any medical procedure, bio-stimulating filler injections carry certain risks and potential side effects. While these risks are generally low, it is important to be aware of them. The specific risks and side effects can vary depending on the type of filler used and individual factors. Here are some possible risks and side effects associated with bio-stimulating filler injections:

  • Injection-related reactions: These may include temporary redness, swelling, bruising, or tenderness at the injection site. These reactions are usually mild and subside within a few days.
  • Allergic reactions: Although rare, some individuals may have an allergic reaction to the filler material. Symptoms may include itching, rash, hives, or swelling in areas beyond the injection site. If you experience any allergic reactions, it is important to seek immediate medical attention.
  • Infection: Although proper sterilization techniques are followed during the procedure, there is a risk of infection at the injection site. It is important to choose a reputable and experienced healthcare professional to minimize this risk.
  • Nodule formation: In some cases, small lumps or nodules may form at the injection site. These can usually be felt and may require additional treatment, such as massage or injection of medication, to smooth them out.
  • Migration or asymmetry: There is a small possibility that the injected filler may shift from its intended location or cause asymmetry. This can usually be corrected with additional treatments or adjustments.
  • Granuloma formation: In rare cases, the body may react to the filler material by forming granulomas, which are small nodules of inflamed tissue. Granulomas may require medical intervention for resolution.


The number of collagen-stimulating injections needed can vary depending on various factors, such as the specific treatment area, the condition being addressed, and individual response to the injections. During a consultation, we will evaluate and discuss your desired outcomes.

In some cases, a single treatment session may be sufficient to achieve the desired results. However, for more significant improvements or specific concerns, multiple treatment sessions may be recommended. These sessions are typically spaced several weeks apart to allow for optimal collagen production and to assess the progress of the treatment.


Unlike dermal fillers, which can be dissolved with hyaluronidase, collagen-stimulating injections cannot be reversed.


Results with bio-stimulating injections can be seen around 6 to 9 months after treatment, and some patients may choose to have additional treatments within 12 to 18 months. However, it’s important to note that individual results may vary. The duration of results can be influenced by various factors such as the specific product used, the treatment area, the individual’s age, lifestyle factors, and overall skin health.

While bio-stimulating injections are designed to stimulate collagen production and provide longer-lasting effects compared to traditional dermal fillers, the actual duration of results can differ from person to person. Factors such as natural ageing processes, lifestyle choices, and the ongoing health of the skin can affect how long the results are maintained. Most leading brands will stipulate lasting 18-24 months.


Typically, the cost of bio-stimulator injections depends on the amount, and you can view our pricing list here.

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